Behavioral changes in male mice fed a high-fat diet are associated with IL-1β expression in specific brain regions.

@article{AlmeidaSuhett2017BehavioralCI,
  title={Behavioral changes in male mice fed a high-fat diet are associated with IL-1β expression in specific brain regions.},
  author={Camila P. Almeida-Suhett and Alice Graham and Yifan Chen and Patricia Anne Deuster},
  journal={Physiology & behavior},
  year={2017},
  volume={169},
  pages={
          130-140
        }
}
High-fat diet (HFD)-induced obesity is associated with not only increased risk of metabolic and cardiovascular diseases, but cognitive deficit, depression and anxiety disorders. Obesity also leads to low-grade peripheral inflammation, which plays a major role in the development of metabolic alterations. Previous studies suggest that obesity-associated… CONTINUE READING