Behavioral changes during exposure to 1,1,1-trichloroethane: time-course and relationship to blood solvent levels.

@article{Mackay1987BehavioralCD,
  title={Behavioral changes during exposure to 1,1,1-trichloroethane: time-course and relationship to blood solvent levels.},
  author={Cynthia J Mackay and L V Campbell and Aban Meyer Samuel and K J Alderman and C. Idzikowski and H. K. Wilson and David Gompertz},
  journal={American journal of industrial medicine},
  year={1987},
  volume={11 2},
  pages={223-39}
}
We report the results of an exposure chamber study in which volunteers were exposed to 0, 950 mg.m-3 (175 ppm) and 1,990 mg.m-3 (350 ppm) of 1,1,1-trichloroethane for 3.5 hours. The time-course of the behavioral changes and the relationship to blood concentrations of 1,1,1-trichloroethane were investigated. A pattern of performance deficits consistent with earlier work was found for some of the tests of psychomotor performance. The time-course of these appeared to be rapid, occurring in some… CONTINUE READING