Behavioral biochemical and neuroendocrine concomitants of lactate-induced panic anxiety.

@article{Boer1989BehavioralBA,
  title={Behavioral biochemical and neuroendocrine concomitants of lactate-induced panic anxiety.},
  author={Johan A. den Boer and Herman G. M. Westenberg and Andr{\'e} A. Klompmakers and L E van Lint},
  journal={Biological psychiatry},
  year={1989},
  volume={26 6},
  pages={612-22}
}
In a single-blind study using sodium lactate infusions to provoke panic attacks, 11 of 15 patients with panic disorder panicked with lactate. None of the 15 control subjects panicked during lactate administration. Before receiving lactate, higher preinfusion anxiety levels were present in the patient group as compared to controls. Preinfusion Acute Panic Inventory (API) scores were significantly higher in patients who panicked compared to nonpanicking patients. In addition, patients who… CONTINUE READING

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