Behavioral and pharmacological specificity of the feeding elicited by cholinergic stimulation of the substantia nigra in the rat.

@article{Winn1983BehavioralAP,
  title={Behavioral and pharmacological specificity of the feeding elicited by cholinergic stimulation of the substantia nigra in the rat.},
  author={Philip Winn and Aine Farrell and A Maconick and Trevor W. Robbins},
  journal={Behavioral neuroscience},
  year={1983},
  volume={97 5},
  pages={794-809}
}
Microinjections of the cholinergic agonist carbachol into anterior substantia nigra dose dependently increased food intake in satiated rats. This resulted from a prolongation of the duration of eating. In the absence of food, those doses of carbachol that stimulated food intake (.1 and .5 microgram) had no effect on any other response examined, including gnawing, drinking, locomotion, grooming, sniffing, and rearing. The effect of carbachol depended on the degree of prior food deprivation, but… CONTINUE READING