Behavioral and neuropharmacological characterization of nicotine as a conditional stimulus.

@article{Murray2007BehavioralAN,
  title={Behavioral and neuropharmacological characterization of nicotine as a conditional stimulus.},
  author={Jennifer E Murray and Rick A Bevins},
  journal={European journal of pharmacology},
  year={2007},
  volume={561 1-3},
  pages={91-104}
}
In rats, the pharmacological (interoceptive) effects of 0.4 mg/kg nicotine can serve as a conditional stimulus in a Pavlovian conditioning task. Nicotine administration is paired with intermittent access to a liquid sucrose unconditional stimulus; sucrose is withheld on saline sessions. An increase in sucrose receptacle entries (goal tracking) on nicotine sessions indicates conditioning. Rats were trained on a nicotine dose ((-)-1-Methyl-2-(3-pyridyl)pyrrolidine; 0.1, 0.2, or 0.4 mg base/kg, s… CONTINUE READING
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A description of the nicotine stimulus and tests of its generalization to amphetamine

  • W. T. Chance, D. Murfi n, G. M. Krynock, J. A. Rosecrans
  • Psychopharmacology
  • 1977
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