Behavioral and monoaminergic changes after lindane exposure in developing rats.

@article{Rivera1998BehavioralAM,
  title={Behavioral and monoaminergic changes after lindane exposure in developing rats.},
  author={Sulay Rivera and Rui Rosa and E. Pintos Mart{\'i}nez and Cristina Su{\~n}ol and Mari{\'a}n Serrano and Miguel Vendrell and Eduard Rodr{\'i}guez-Farr{\'e} and C. Bartual Sanfeliu},
  journal={Neurotoxicology and teratology},
  year={1998},
  volume={20 2},
  pages={155-60}
}
The effects of lindane on behavior and central monoaminergic systems were studied in rat pups at 15 days of postnatal age. Pups were previously given nonconvulsant lindane PO doses, either a single 20 mg/kg or 7-day repeated 10 mg/kg doses. Both treatment schedules improved the passive avoidance acquisition but only the acute administration prolonged the step-through latency. Acute lindane decreased the motor activity, whereas the repeated dosing increased it. Increases of the ratio 5-HIAA… CONTINUE READING