Behavioral and biochemical evidence for a nonessential 5-HT2A component of the ibogaine-induced discriminative stimulus.

Abstract

In the present investigation, the ability of two known hallucinogens, lysergic acid dimethylamide (LSD) and (-)-2,5-dimethoxy-4-methyl-amphetamine (DOM), to substitute for the ibogaine-induced discriminative stimulus (10 mg/kg I.P., 60 min presession) was assessed in Fischer-344 rats. In these subjects, intermediate levels of generalization were observed to… (More)

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@article{Helsley1998BehavioralAB, title={Behavioral and biochemical evidence for a nonessential 5-HT2A component of the ibogaine-induced discriminative stimulus.}, author={Scott E. Helsley and D Fiorella and Ronald Rabin and J. C. Winter}, journal={Pharmacology, biochemistry, and behavior}, year={1998}, volume={59 2}, pages={419-25} }