Behavioral and biochemical effects of postnatal parathion exposure in the rat.

@article{Stamper1988BehavioralAB,
  title={Behavioral and biochemical effects of postnatal parathion exposure in the rat.},
  author={C R Stamper and Walter Balduini and Sheldon D. Murphy and Lucio Guido Costa},
  journal={Neurotoxicology and teratology},
  year={1988},
  volume={10 3},
  pages={261-6}
}
Preweanling rat pups were exposed daily to parathion (1.3 mg/kg or 1.9 mg/kg) or vehicle (corn oil) on postnatal days 5-20, a time period critical to development of behavioral and biochemical parameters of the cholinergic nervous system. This exposure resulted in dose-dependent reductions in acetylcholinesterase activity and muscarinic receptor binding in the cortex. During the preweanling period, there were no differences among the groups in most reflex measures, eye opening or incisor… CONTINUE READING

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