Behavioral and Neurochemical Characteristics of Two Months Old WAG/Rij Rats with Genetic Absence Epilepsy

@article{Fedosova2015BehavioralAN,
  title={Behavioral and Neurochemical Characteristics of Two Months Old WAG/Rij Rats with Genetic Absence Epilepsy},
  author={E. Fedosova and K. Sarkisova and V. Kudrin and V. Narkevich and A. Bazyan},
  journal={Clinical and experimental neurology},
  year={2015},
  volume={3},
  pages={32-44}
}
  • E. Fedosova, K. Sarkisova, +2 authors A. Bazyan
  • Published 2015
  • Medicine
  • Clinical and experimental neurology
    • WAG/Rij rats are genetic animal model of absence epilepsy with comorbidity of depression. The first spike-wave discharges (SWDs) in WAG/Rij rats begin to appear at the age of 2-3 months and are fully manifested by 5-6 months. Occurrence of SWDs in the EEG is the main index of absence epilepsy. Previously it has been shown that the extensive absence epilepsy in 5-6 months old WAG/Rij rats is accompanied by decrease of dopamine and its metabolites concentrations in the meso-cortico-limbic and… CONTINUE READING
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    SHOWING 1-10 OF 62 REFERENCES
    Dopamine-dependent nature of depression-like behavior in WAG/Rij rats with genetic absence epilepsy
    • 40
    Depressive-like behavioral alterations and c-fos expression in the dopaminergic brain regions in WAG/Rij rats with genetic absence epilepsy
    • 86
    • Highly Influential
    Neurochemical and Behavioral Features in Genetic Absence Epilepsy and in Acutely Induced Absence Seizures
    • 12
    • PDF
    Behavioral characteristics of WAG/Rij rats susceptible and non-susceptible to audiogenic seizures
    • 45
    [Neurochemical mechanisms of depression-like behavior in WAG/Rij rats].
    • 9
    [Neurochemical mechanisms of depression-like behavior in WAG/Rij rats].
    • 10
    [Does antiabsence drug ethosuximide exert antidepressant effect?].
    • 1
    Does antiabsence drug ethosuximide exert antidepressant effect
    • 2
    Anxiety-like behaviors in pre-pubertal rats of the Flinders Sensitive Line (FSL) and Wistar-Kyoto (WKY) animal models of depression
    • 54
    • PDF
    Reduced exploratory activity of audiogenic seizures suceptible Wistar rats
    • 49