Behavioral alterations of zebrafish larvae after early embryonic exposure to ketamine

@article{Felix2016BehavioralAO,
  title={Behavioral alterations of zebrafish larvae after early embryonic exposure to ketamine},
  author={L. E. M. Felix and Lu{\'i}s M. Antunes and Ana Maria Coimbra and Ana Maria Valentim},
  journal={Psychopharmacology},
  year={2016},
  volume={234},
  pages={549-558}
}
Ketamine has been associated with pediatric risks that include neurocognitive impairment and long-term behavioral disorders. However, the neurobehavioral effects of ketamine exposure in early development remain uncertain. This study aimed to test stage- and dose-dependent effects of ketamine exposure on certain brain functions by evaluating alterations in locomotion, anxiety-like and avoidance behaviors, as well as socialization. Embryos were exposed to different concentrations of ketamine (0… CONTINUE READING