Behavior of itraconazole and benzyl alcohol in aqueous solution containing nonionic surfactants.

Abstract

In order to investigate the behavior of itraconazole and benzyl alcohol in aqueous solution containing surfactants, the distribution of itraconazole and benzyl alcohol between the micellar and aqueous phases was determined and the partition of itraconazole between the hydrophilic and lipophilic moieties in micelles was measured. From these experiments, we… (More)

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