Behçet's disease and antibody titers to various heat-shock protein 60s.

@article{Tanaka1999BehetsDA,
  title={Behçet's disease and antibody titers to various heat-shock protein 60s.},
  author={Toshihiro Tanaka and Naoyuki Yamakawa and Noboru Koike and Jun Suzuki and Fumio Mizuno and Masahiko Usui},
  journal={Ocular immunology and inflammation},
  year={1999},
  volume={7 2},
  pages={69-74}
}
It has been suggested that the 65 kDa heat-shock protein (HSP) of Streptococcus in recurrent aphthae within the oral cavity may be involved in the uveoretinitis of Behçet's disease, possibly through sensitization of the immune system. To investigate this possibility, we examined serum antibody titers for various members of the 60 kDa family of HSPs and their implications with regard to a role for HSP60s in Behçet's disease. We isolated HSP60 of Streptococcus pyogenes from the margin of oral… CONTINUE READING