Behçet's disease: familial clustering and immunogenetics.

  title={Behçet's disease: familial clustering and immunogenetics.},
  author={Pieranna Fietta},
  journal={Clinical and experimental rheumatology},
  volume={23 4 Suppl 38},
Behçet's disease (BD) is a relapsing, multisystemic inflammatory disorder, characterized by major symptoms consisting of recurrent orogenital ulcerations, eye and skin lesions. Other clinical features may include musculoskeletal, vascular, gastrointestinal, renal, cardiopulmonary or neurological involvement. Vasculitis affecting all types and sizes of blood vessels is the main histopathologic process, in a third of cases complicated by thrombosis. The etiopathogenesis is presently unknown, but… CONTINUE READING


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