Bee venom-derived antimicrobial peptide melectin has broad-spectrum potency, cell selectivity, and salt-resistant properties

  title={Bee venom-derived antimicrobial peptide melectin has broad-spectrum potency, cell selectivity, and salt-resistant properties},
  author={S. Ko and Eunji Park and Alina Asandei and Jee-Young Choi and Seung-Chul Lee and C. Seo and T. Luchian and Yoonkyung Park},
  journal={Scientific Reports},
Antimicrobial peptides have attracted attention as alternatives to conventional antibiotics. Previously, a novel antimicrobial peptide, melectin, consisting of 18 amino acids was isolated from the venom of a bee, Melecta albifrons . Here, we investigated the antibacterial activity of melectin against drug-resistant bacteria. Melectin showed broad-spectrum antimicrobial activity but low cytotoxicity and no hemolytic activity. Melectin maintained its antimicrobial activity at physiological salt… Expand
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  • R. Hancock
  • Biology, Medicine
  • The Lancet. Infectious diseases
  • 2001
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