Bedtime administration of graded-release diltiazem in patients with inadequate BP control: a tolerability and efficacy study.

BACKGROUND Achievement of target BP is a challenge in patients attending family practice. The long duration between administration of the last bedtime dose of antihypertensive medication and the physiologic early morning surge in BP makes it difficult to achieve satisfactory BP control. OBJECTIVE To determine whether a new graded-release preparation of… CONTINUE READING