Bedside multimarker testing for risk stratification in chest pain units: The chest pain evaluation by creatine kinase-MB, myoglobin, and troponin I (CHECKMATE) study.

@article{Newby2001BedsideMT,
  title={Bedside multimarker testing for risk stratification in chest pain units: The chest pain evaluation by creatine kinase-MB, myoglobin, and troponin I (CHECKMATE) study.},
  author={L K Newby and Alan B. Storrow and W. Brian Gibler and J L Garvey and J F Tucker and A L Kaplan and D H Schreiber and R H Tuttle and S E McNulty and E M Ohman},
  journal={Circulation},
  year={2001},
  volume={103 14},
  pages={1832-7}
}
  • L K Newby, Alan B. Storrow, +7 authors E M Ohman
  • Published 2001 in Circulation
BACKGROUND Earlier, rapid evaluation in chest pain units may make patient care more efficient. A multimarker strategy (MMS) testing for several markers of myocardial necrosis with different time-to-positivity profiles also may offer clinical advantages. METHODS AND RESULTS We prospectively compared bedside quantitative multimarker testing versus local laboratory results (LL) in 1005 patients in 6 chest pain units. Myoglobin, creatine kinase-MB, and troponin I were measured at 0, 3, 6, 9 to 12… CONTINUE READING