Beclin-1–p53 interaction is crucial for cell fate determination in embryonal carcinoma cells

@inproceedings{Tripathi2014Beclin1p53II,
  title={Beclin-1–p53 interaction is crucial for cell fate determination in embryonal carcinoma cells},
  author={Rakshamani Tripathi and Dipankar Ash and Chandrima Shaha},
  booktitle={Journal of cellular and molecular medicine},
  year={2014}
}
Emerging interest on the interrelationship between the apoptotic and autophagy pathways in the context of cancer chemotherapy is providing exciting discoveries. Complexes formed between molecules from both pathways present potential targets for chemotherapeutics design as disruption of such complexes could alter cell survival. This study demonstrates an important role of Beclin-1 and p53 interaction in cell fate decision of human embryonal carcinoma cells. The findings provide evidence for p53… CONTINUE READING
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