Bead-linked proteoliposomes: a reconstitution method for nmr analyses of membrane protein-ligand interactions.

@article{Yokogawa2005BeadlinkedPA,
  title={Bead-linked proteoliposomes: a reconstitution method for nmr analyses of membrane protein-ligand interactions.},
  author={Mariko Yokogawa and Koh Takeuchi and Ichio Shimada},
  journal={Journal of the American Chemical Society},
  year={2005},
  volume={127 34},
  pages={12021-7}
}
Structural information about the interactions between membrane proteins and their ligands provides insights into the membrane protein functions. A variety of surfactants have been used for structural analyses of membrane proteins, and in some cases, they yielded successful results. However, the use of surfactants frequently increases the conformational instability of membrane proteins and distorts their normal function. Here, we propose a new strategy of membrane protein reconstitution into… CONTINUE READING

From This Paper

Topics from this paper.
5 Citations
0 References
Similar Papers