Bcl10 and MALT1, independent targets of chromosomal translocation in malt lymphoma, cooperate in a novel NF-kappa B signaling pathway.

Abstract

At least two distinct recurrent chromosomal translocations have been implicated in the pathogenesis of MALT lymphoma. The first, t(1;14), results in the transfer of the entire Bcl10 gene to chromosome 14 wherein Bcl10 expression is inappropriately stimulated by the neighboring Ig enhancer. The second, t(11;18), results in the synthesis of a novel fusion… (More)

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Cite this paper

@article{Lucas2001Bcl10AM, title={Bcl10 and MALT1, independent targets of chromosomal translocation in malt lymphoma, cooperate in a novel NF-kappa B signaling pathway.}, author={Peter C. Lucas and Masakatu Yonezumi and Naohiro Inohara and Linda M. McAllister-Lucas and Mohamed E Abazeed and Felicia F Chen and Shoji Yamaoka and Masao Seto and Gast{\'o}n E N{\'u}{\~n}ez}, journal={The Journal of biological chemistry}, year={2001}, volume={276 22}, pages={19012-9} }