Bcl-6 predicts improved prognosis in primary central nervous system lymphoma.

@article{Levy2008Bcl6PI,
  title={Bcl-6 predicts improved prognosis in primary central nervous system lymphoma.},
  author={Oren A. Levy and Lisa M DeAngelis and Daniel A Filippa and Katherine S. Panageas and Lauren Eileen Abrey},
  journal={Cancer},
  year={2008},
  volume={112 1},
  pages={151-6}
}
BACKGROUND In systemic non-Hodgkin lymphoma (NHL), tumors that resemble germinal center B-cells are less aggressive than tumors that resemble postgerminal center B-cells. However, the value of B-cell differentiation markers in primary central nervous system lymphoma (PCNSL) is less clear. The objectives of this study were to characterize the immunophenotypes of PCNSL samples and to determine their utility in predicting clinical outcomes. METHODS The immunohistochemical staining profile of… CONTINUE READING

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