Bcl-2 modulates telomerase activity.

@article{Mandal1997Bcl2MT,
  title={Bcl-2 modulates telomerase activity.},
  author={Mahitosh Mandal and Rakesh Kumar},
  journal={The Journal of biological chemistry},
  year={1997},
  volume={272 22},
  pages={
          14183-7
        }
}
Apoptosis is a physiological mechanism of cell death that plays an important role in the regulation of tissue homeostasis. The regulation of apoptosis is a complex process and involves a number of gene products including the survival factor Bcl-2, which has been found to be frequently deregulated in human cancers. In addition to deregulation of apoptosis, the process of neoplasia is also believed to be driven by the activation of telomerase, a ribonucleoprotein complex that adds telomeric… CONTINUE READING

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