Bcl-2 family of proteins as therapeutic targets in genitourinary neoplasms.

@article{Hall2013Bcl2FO,
  title={Bcl-2 family of proteins as therapeutic targets in genitourinary neoplasms.},
  author={Connor P. Hall and Sarah M. Troutman and Douglas K. Price and William D. Figg and Min Ho Kang},
  journal={Clinical genitourinary cancer},
  year={2013},
  volume={11 1},
  pages={10-9}
}
INTRODUCTION Overexpression of antiapoptotic B-cell lymphoma (Bcl-2) proteins confers the dysregulation of apoptosis and results in drug resistance in a variety of cancers, including those of the genitourinary tract. Inhibitors that target prosurvival Bcl-2 proteins are in preclinical and clinical development. The objective of this review is to assess the… CONTINUE READING