Bcl-2-expressing oligodendrocytes in multiple sclerosis lesions.

@article{Kuhlmann1999Bcl2expressingOI,
  title={Bcl-2-expressing oligodendrocytes in multiple sclerosis lesions.},
  author={Tanja Kuhlmann and C F Lucchinetti and Uwe K. Zettl and Andreas Bitsch and Hans Lassmann and Wolfgang Br{\"u}ck},
  journal={Glia},
  year={1999},
  volume={28 1},
  pages={
          34-9
        }
}
Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system leading to selective destruction of myelin sheaths and/or oligodendrocytes. The immunological mechanisms responsible for myelin destruction and the primary target of the immune response have not yet been identified. Prior studies have reported a variable degree of oligodendrocyte preservation in actively demyelinating lesions. We have previously demonstrated that oligodendrocyte survival is heterogenous and… CONTINUE READING

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