Bcl-2 and Bcl-2-related proteins in apoptosis regulation.

  title={Bcl-2 and Bcl-2-related proteins in apoptosis regulation.},
  author={Lawrence H. Boise and Alexander R. Gottschalk and Jose Quintans and Craig B Thompson},
  journal={Current topics in microbiology and immunology},
In this review we have discussed the importance of Bcl-2 and related proteins in the regulation of apoptotic cell death in mammalian systems. It is clear that Bcl-2 plays a critical role in controlling many forms of PCD. Bcl-2 seems to have particular significance in lymphocyte development and the function of the immune system. We have also discussed the… CONTINUE READING