Bayesian variable and model selection methods for genetic association studies.

@article{Fridley2009BayesianVA,
  title={Bayesian variable and model selection methods for genetic association studies.},
  author={Brooke L. Fridley},
  journal={Genetic epidemiology},
  year={2009},
  volume={33 1},
  pages={27-37}
}
Variable selection is growing in importance with the advent of high throughput genotyping methods requiring analysis of hundreds to thousands of single nucleotide polymorphisms (SNPs) and the increased interest in using these genetic studies to better understand common, complex diseases. Up to now, the standard approach has been to analyze the genotypes for each SNP individually to look for an association with a disease. Alternatively, combinations of SNPs or haplotypes are analyzed for… CONTINUE READING