Bayesian sampling of genomic rearrangement scenarios via double cut and join

  title={Bayesian sampling of genomic rearrangement scenarios via double cut and join},
  author={Istv{\'a}n Mikl{\'o}s and {\'E}ric Tannier},
  volume={26 24},
MOTIVATION When comparing the organization of two genomes, it is important not to draw conclusions on their modes of evolution from a single most parsimonious scenario explaining their differences. Better estimations can be obtained by sampling many different genomic rearrangement scenarios. For this problem, the Double Cut and Join (DCJ) model, while less relevant, is computationally easier than the Hannenhalli-Pevzner (HP) model. Indeed, in some special cases, the total number of DCJ sorting… 

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