Bayesian multi-loci association method : allowing for higher-order interaction in association studies

@inproceedings{Albrechtsen2007BayesianMA,
  title={Bayesian multi-loci association method : allowing for higher-order interaction in association studies},
  author={Anders Albrechtsen and Sofie Castella and Gitte Andersen and Torben Hansen and Oluf Pedersen and R. Nielsen},
  year={2007}
}
For most common diseases with heritable components, there is not a single or a few single nucleotide polymorphisms (SNPs) that explain most of the variance for these disorders. Instead, much of the variance may be caused by interactions (epistasis) among multiple SNPs or interactions with environmental conditions. We present a new powerful statistical model for analyzing and interpreting genomic data that influence multifactorial phenotypic traits with a complex and likely polygenic inheritance… CONTINUE READING