Bayesian modeling of recombination events in bacterial populations

  title={Bayesian modeling of recombination events in bacterial populations},
  author={Pekka Marttinen and Adam Baldwin and William P. Hanage and Chris Dowson and Eshwar Mahenthiralingam and Jukka Corander},
  journal={BMC Bioinformatics},
  pages={421 - 421}
We consider the discovery of recombinant segments jointly with their origins within multilocus DNA sequences from bacteria representing heterogeneous populations of fairly closely related species. The currently available methods for recombination detection capable of probabilistic characterization of uncertainty have a limited applicability in practice as the number of strains in a data set increases. We introduce a Bayesian spatial structural model representing the continuum of origins over… CONTINUE READING