Bayesian model comparison in genetic association analysis: linear mixed modeling and SNP set testing.

@article{Wen2015BayesianMC,
  title={Bayesian model comparison in genetic association analysis: linear mixed modeling and SNP set testing.},
  author={Xiaoquan Wen},
  journal={Biostatistics},
  year={2015},
  volume={16 4},
  pages={701-12}
}
We consider the problems of hypothesis testing and model comparison under a flexible Bayesian linear regression model whose formulation is closely connected with the linear mixed effect model and the parametric models for Single Nucleotide Polymorphism (SNP) set analysis in genetic association studies. We derive a class of analytic approximate Bayes factors and illustrate their connections with a variety of frequentist test statistics, including the Wald statistic and the variance component… CONTINUE READING
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Robust Bayesian FDR control with Bayes factors

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  • arXiv preprint arXiv:1311.3981.
  • 2013
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