Bayesian hierarchical modeling for subject-level response classification in peptide microarray immunoassays.

Abstract

The peptide microarray immunoassay simultaneously screens sample serum against thousands of peptides, determining the presence of antibodies bound to array probes. Peptide microarrays tiling immunogenic regions of pathogens (e.g., envelope proteins of a virus) are an important high throughput tool for querying and mapping antibody binding. Because of the… (More)
DOI: 10.1111/biom.12523

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