Bayesian evidence synthesis to extrapolate survival estimates in cost-effectiveness studies.

@article{Demiris2006BayesianES,
  title={Bayesian evidence synthesis to extrapolate survival estimates in cost-effectiveness studies.},
  author={Nikolaos Demiris and Linda D. Sharples},
  journal={Statistics in medicine},
  year={2006},
  volume={25 11},
  pages={1960-75}
}
This paper is concerned with survival extrapolation that represents an integral part of cost-effectiveness analysis. In the absence of long-term survival estimates from randomized clinical trials or meta-analysis we show how age-sex matched U.K. population data can additionally be used to estimate survival patterns. We adopt a Bayesian approach and we synthesize evidence from different sources such as patient registries, U.K. population statistics and meta-analyses. We also present methodology… CONTINUE READING