Bayesian analysis of linkage between genetic markers and quantitative trait loci. I. Prior knowledge

@article{Hoeschele1993BayesianAO,
  title={Bayesian analysis of linkage between genetic markers and quantitative trait loci. I. Prior knowledge},
  author={Ina Hoeschele and P M Vanraden},
  journal={Theoretical and Applied Genetics},
  year={1993},
  volume={85},
  pages={953-960}
}
Prior information on gene effects at individual quantitative trait loci (QTL) and on recombination rates between marker loci and QTL is derived. The prior distribution of QTL gene effects is assumed to be exponential with major effects less likely than minor ones. The prior probability of linkage between a marker and another single locus is a function of… CONTINUE READING