Bayesian analysis of RNA sequencing data by estimating multiple shrinkage priors.

@article{Wiel2013BayesianAO,
  title={Bayesian analysis of RNA sequencing data by estimating multiple shrinkage priors.},
  author={Mark A. van de Wiel and Gwena{\"e}l G. R. Leday and L. Pardo and H{\aa}vard Rue and Aad W. van der Vaart and Wessel N van Wieringen},
  journal={Biostatistics},
  year={2013},
  volume={14 1},
  pages={113-28}
}
Next generation sequencing is quickly replacing microarrays as a technique to probe different molecular levels of the cell, such as DNA or RNA. The technology provides higher resolution, while reducing bias. RNA sequencing results in counts of RNA strands. This type of data imposes new statistical challenges. We present a novel, generic approach to model… CONTINUE READING

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