Bax, Bcl2, and p53 Differentially Regulate Neomycin- and Gentamicin-Induced Hair Cell Death in the Zebrafish Lateral Line

Abstract

Sensorineural hearing loss is a normal consequence of aging and results from a variety of extrinsic challenges such as excessive noise exposure and certain therapeutic drugs, including the aminoglycoside antibiotics. The proximal cause of hearing loss is often death of inner ear hair cells. The signaling pathways necessary for hair cell death are not fully… (More)
DOI: 10.1007/s10162-013-0404-1

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@article{Coffin2013BaxBA, title={Bax, Bcl2, and p53 Differentially Regulate Neomycin- and Gentamicin-Induced Hair Cell Death in the Zebrafish Lateral Line}, author={Allison B. Coffin and Edwin W. Rubel and David W. Raible}, journal={Journal of the Association for Research in Otolaryngology}, year={2013}, volume={14}, pages={645-659} }