Bax, Bcl-2, fas and Fas-L antigen expression in human seminoma: correlation with the apoptotic index.

@article{Grobholz2002BaxBF,
  title={Bax, Bcl-2, fas and Fas-L antigen expression in human seminoma: correlation with the apoptotic index.},
  author={Rainer Grobholz and H. Zentgraf and K. -U. K{\"o}hrmann and Uwe Bleyl},
  journal={APMIS : acta pathologica, microbiologica, et immunologica Scandinavica},
  year={2002},
  volume={110 10},
  pages={724-32}
}
Apoptosis plays a crucial role in the regulation of spermatogenesis in male germ cells and is, at least in part, modulated by Bcl-2, Bax, and the Fas pathway. Seminomas have a favourable outcome and respond to radio-/chemotherapy with an increased rate of apoptosis. The expression of Bax, Bcl-2, Fas and Fas-ligand (Fas-L) in human seminoma was evaluated and… CONTINUE READING