Bat-derived influenza-like viruses H17N10 and H18N11.

  title={Bat-derived influenza-like viruses H17N10 and H18N11.},
  author={Yan Yan Wu and Boris Tefsen and Yi Shi and George F. Gao},
  journal={Trends in microbiology},
  volume={22 4},
Shorebirds and waterfowls are believed to be the reservoir hosts for influenza viruses, whereas swine putatively act as mixing vessels. The recent identification of two influenza-like virus genomes (designated H17N10 and H18N11) from bats has challenged this notion. A crucial question concerns the role bats might play in influenza virus ecology. Structural and functional studies of the two major surface envelope proteins, hemagglutinin (HA) and neuraminidase (NA), demonstrate that neither has… CONTINUE READING