Basophils are not the key antigen-presenting cells in allergic patients.

@article{EcklDorna2012BasophilsAN,
  title={Basophils are not the key antigen-presenting cells in allergic patients.},
  author={Julia Eckl-Dorna and Adolf Ellinger and Katharina Blatt and Viviane Ghanim and Irene Steiner and Margit Pavelka and Peter Valent and Rudolf Valenta and Verena Niederberger},
  journal={Allergy},
  year={2012},
  volume={67 5},
  pages={601-8}
}
BACKGROUND Recent data obtained in mouse models have initiated a controversy whether basophils are the key antigen-presenting cells (APCs) in allergy. Here, we investigate whether basophils are of importance for the presentation of allergen and the induction of T cell proliferation in allergic patients. METHODS T cells, basophils, and APCs depleted of… CONTINUE READING