Basophil effector function and homeostasis during helminth infection.

  title={Basophil effector function and homeostasis during helminth infection.},
  author={Caspar Ohnmacht and David Voehringer},
  volume={113 12},
Basophils are effector cells of the innate immune system that are associated with allergic inflammation and infections with helminth parasites. However, their development and in vivo functions are largely unknown. Here, we characterize basophil development, turnover, tissue localization, and effector function during infection with the helminth Nippostrongylus brasiliensis. Our results demonstrate that under homeostatic conditions basophils have a lifespan of about 60 hours. N brasiliensis… CONTINUE READING


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sinophils develop in distinct stages and are recruited to peripheral sites by alternatively activated macrophages

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