Basomedial amygdala mediates top–down control of anxiety and fear

@inproceedings{Adhikari2015BasomedialAM,
  title={Basomedial amygdala mediates top–down control of anxiety and fear},
  author={Avishek Adhikari and Talia N. Lerner and J. Barnett Finkelstein and Sally M Pak and Joshua H. Jennings and Thomas J Davidson and Emily A. Ferenczi and Lisa A. Gunaydin and Julie J. Mirzabekov and Li Xuan Ye and Sung-Yon Kim and Anna Lei and Karl Deisseroth},
  booktitle={Nature},
  year={2015}
}
Anxiety-related conditions are among the most difficult neuropsychiatric diseases to treat pharmacologically, but respond to cognitive therapies. There has therefore been interest in identifying relevant top-down pathways from cognitive control regions in medial prefrontal cortex (mPFC). Identification of such pathways could contribute to our understanding of the cognitive regulation of affect, and provide pathways for intervention. Previous studies have suggested that dorsal and ventral mPFC… CONTINUE READING
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