Basolateral P2X receptors mediate inhibition of NaCl transport in mouse medullary thick ascending limb (mTAL).

@article{Marques2012BasolateralPR,
  title={Basolateral P2X receptors mediate inhibition of NaCl transport in mouse medullary thick ascending limb (mTAL).},
  author={Rita D. Marques and Pauline I A de Bruijn and Mads V. Sorensen and Markus Bleich and Helle A Praetorius and Jens Leipziger},
  journal={American journal of physiology. Renal physiology},
  year={2012},
  volume={302 4},
  pages={F487-94}
}
Extracellular nucleotides regulate epithelial transport via luminal and basolateral P2 receptors. Renal epithelia express multiple P2 receptors, which mediate significant inhibition of solute absorption. Recently, we identified several P2 receptors in the medullary thick ascending limb (mTAL) including luminal and basolateral P2Y(2) receptors (Jensen ME, Odgaard E, Christensen MH, Praetorius HA, Leipziger J. J Am Soc Nephrol 18: 2062-2070, 2007). In addition, we found evidence for a basolateral… CONTINUE READING

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