Basilar impression and osteogenesis imperfecta: a 21-year retrospective review of outcomes in 20 patients.

  title={Basilar impression and osteogenesis imperfecta: a 21-year retrospective review of outcomes in 20 patients.},
  author={Ahmed Gadam Ibrahim and H. Alan Crockard},
  journal={Journal of neurosurgery. Spine},
  volume={7 6},
OBJECT Basilar impression (BI) secondary to osteogenesis imperfecta (OI) is a rare but debilitating condition that is often progressive unless it is halted. More recently, ventral decompression surgery has been advocated for this condition. This study is a retrospective review of the 21-year experience of ventral decompression surgery and dorsal occipitocervical fixation in patients with BI secondary to OI and is the largest patient series reported to date. METHODS Twenty patients treated… 

Figures and Tables from this paper

Severe Basilar impression in osteogenesis imperfecta treated with halo gravity traction, occipitocervicothoracic fusion, foramen magnum and upper cervical decompression and expansive duroplasty: a technical note
A case of a 16-years-old patient, diagnosed with OI and BI, treated with halo traction, occipito-cervico-thoracic fixation, foramen magnum and upper cervical decompression, and expansive duroplasty is presented.
Endoscopic Image-Guided Transcervical Odontoidectomy: Outcomes of 15 Patients With Basilar Invagination
ETO may be a valid treatment for patients with symptomatic irreducible basilar invagination that avoids some of the morbidity of transoral surgery and leads to long-term improvement in myelopathy.
Management of Acute Cervical Compression Fractures in Two Patients With Osteogenesis Imperfecta
A combined anterior/posterior decompression and fusion of the subaxial cervical spine is feasible in the fragile OI population and certain isolated compression fractures in this same patient population may be managed nonoperatively.
Sublabial Approach for the Treatment of Symptomatic Basilar Impression in a Patient With Klippel-Feil Syndrome
The sublabial route is an alternative approach for anterior decompression in patients with symptomatic basilar impression and altered anatomic circumstances such as that caused by Klippel-Feil syndrome.
Basilar Impression and Invagination
Basilar impression (secondary/acquired) and invagination (primary) develop when the odontoid process of C2 migrates into the foramen magnum, causing compression of the brainstem and upper cervical
Utility of the clivo-axial angle in assessing brainstem deformity: pilot study and literature review
The thesis that the kyphotic clivo-axial angle (CXA) maybe an important metric for predicting the risk of brainstem and upper spinal cord deformation is supported.
Pseudo-Protrusio Acetabular Deformity in Osteogenesis Imperfecta Patients.
It was showed that acetabular deformity is common in OI patients and is associated with disease severity, and superomedial bulging of the iliopectineal line was the most predictive radiographic sign.
Osteogenesis Imperfecta: A Case-Based Guide to Surgical Decision-Making and Care
Optimizing bone density and strength is recommended through nutritional, bisphosphonate, or other pharmacologic treatments and confirmation through bone density measurement as possible in conjunction with the multidisciplinary team.


Pediatric transoral surgery: indications, complications, and long-term outcome.
It is suggested that although transoral surgery can be effective, it also carries a significant risk of neurological injury in patients with symptomatic spinal cord compression and it is also associated with long-term swallowing and speech difficulties.
The operative management of basilar impression in osteogenesis imperfecta.
Four patients with osteogenesis imperfecta and neurologically significant basilar impression have been treated over the past 8 years. The experience has resulted in changes in our therapeutic
Basilar invagination in osteogenesis imperfecta and related osteochondrodysplasias: medical and surgical management.
Ventral brainstem compression in OI should be treated with ventral decompression, followed by occipitocervical fusion with contoured loop instrumentation to prevent further squamooccipital infolding, however, basilar invagination tends to progress.
Basilar impression in osteogenesis imperfecta. A report of three cases in one family.
Three patients, all members of the same family, with advanced basilar impression complicating osteogenesis imperfecta tarda, are described and the examination of close relatives of patients with Basilar impression and osteogenesisperfecta is emphasised in order to anticipate the onset of severe neurological complications.
Basilar impression complicating osteogenesis imperfecta type IV: the clinical and neuroradiological findings in four cases
Symptoms of cough headache and trigeminal neuralgia occurring in patients with osteogenesis imperfecta are indications for detailed clinical and neuroradiological investigation to document basilar impression.
Vestibular dysfunction in adult patients with osteogenesis imperfecta
It is concluded that vertigo is common in patients with OI, in most cases, it may be secondary to inner ear pathology, and in only some patients does BI explain it.
Osteogenesis Imperfecta
Despite a high rate of complications, intramedullary telescopic roding has proven to be the most successful method for preventing and correcting fractures and deformities of long bones, improving walking capability and leading to successful rehabilitation of even severely affected patients.
  • C. Mayerszky
  • Medicine
    Journal of neurology, neurosurgery, and psychiatry
  • 1949
In the present-day opinion, basilar impi'ession may be last fifteen years it is refetred to mnore often as primary or secondary, and by cases of basilar impression with other associated the occipital bone, atlas, and axis were described defects of development, such as, for example, spina bifida.
Paraplegia in osteogenesis imperfecta. A case report.
Paraplegia occurred in an adolescent girl with osteogenesis imperfecta after chiropractic manipulation due to anterior compression of the cord by spondyloptotic cervical vertebrae and relieved the tethered spinal cord.