Basic therapy for rheumatoid arthritis: nonsteroidal anti-inflammatory drugs.

@article{Daoud1999BasicTF,
  title={Basic therapy for rheumatoid arthritis: nonsteroidal anti-inflammatory drugs.},
  author={K F Daoud and Christopher G. Jackson and Helen J. Williams},
  journal={Comprehensive therapy},
  year={1999},
  volume={25 8-10},
  pages={427-33}
}
Nonsteroidal anti-inflammatory drugs (NSAIDs) are often the initial treatment for rheumatoid arthritis. NSAID-induced inhibition of cyclooxygenase-2 (COX2) and cyclooxygenase-1 appears to correlate with clinical efficacy and toxicity, respectively. Newer NSAIDs with greater COX2 selectivity offer the promise of less toxic therapy.