Basic properties and molecular mechanisms of exogenous chemical carcinogens.

@article{Irigaray2010BasicPA,
  title={Basic properties and molecular mechanisms of exogenous chemical carcinogens.},
  author={Philippe Irigaray and Dominique Belpomme},
  journal={Carcinogenesis},
  year={2010},
  volume={31 2},
  pages={135-48}
}
Exogenous chemical carcinogenesis is an extremely complex multifactorial process during which gene-environment interactions involving chronic exposure to exogenous chemical carcinogens (ECCs) and polymorphisms of cancer susceptibility genes add further complexity. We describe the properties and molecular mechanisms of ECCs that contribute to induce and generate cancer. A basic and specific property of many lipophilic organic ECCs including polycyclic aromatic hydrocarbons and polyhalogenated… CONTINUE READING

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