Basic mechanisms of catastrophic epilepsy -- overview from animal models.

@article{Galanopoulou2013BasicMO,
  title={Basic mechanisms of catastrophic epilepsy -- overview from animal models.},
  author={Aristea S Galanopoulou},
  journal={Brain & development},
  year={2013},
  volume={35 8},
  pages={748-56}
}
Infantile spasms are age-specific seizures of infantile epileptic encephalopathies that are usually associated with poor epilepsy and neurodevelopmental outcomes. The current treatments are not always effective and may be associated with significant side effects. Various mechanisms have been proposed as pathogenic for infantile spasms, including cortical or brainstem dysfunction, disruption of normal cortical-subcortical communications, genetic defects, inflammation, stress, developmental… CONTINUE READING