Basic fibroblast growth factor promotes In vitro survival and cholinergic development of rat septal neurons: Comparison with the effects of nerve growth factor

@article{Grothe1989BasicFG,
  title={Basic fibroblast growth factor promotes In vitro survival and cholinergic development of rat septal neurons: Comparison with the effects of nerve growth factor},
  author={Claudia B. Grothe and D{\"o}rte Otto and Klaus Prof Dr Unsicker},
  journal={Neuroscience},
  year={1989},
  volume={31},
  pages={649-661}
}
The effects of basic fibroblast growth factor and nerve growth factor on survival and transmitter expression of cultured rat embryonic (E18) septal neurons were studied. Two different culture media were used: (i) a horse serum-containing Leibowitz L-15 medium and (ii) a serum-free N1-supplemented Dulbecco's modified Eagle's medium. Addition of basic fibroblast growth factor to either culture medium enhanced neuronal survival in low density cultures after 4 days. The effects of basic fibroblast… CONTINUE READING
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