Basic fibroblast growth factor mediates angiogenic activity in early surgical wounds.

@article{Nissen1996BasicFG,
  title={Basic fibroblast growth factor mediates angiogenic activity in early surgical wounds.},
  author={Nicholas N. Nissen and Peter J. Polverini and Richard L. Gamelli and Luisa A DiPietro},
  journal={Surgery},
  year={1996},
  volume={119 4},
  pages={457-65}
}
BACKGROUND Wound angiogenesis is believed to be initiated by the early rapid release of performed growth factors such as basic fibroblast growth factor (bFGF). However, neither the angiogenic environment of early surgical wounds nor the potential contribution of bFGF to early surgical wound angiogenesis has been investigated. METHODS We collected surgical drain fluid (SDF) from closed suction drains 6 hours to 6 days after operation. SDF was tested for endothelial cell (EC) proliferative and… CONTINUE READING

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