Basic fibroblast growth factor induces down-regulation of alpha-smooth muscle actin and reduction of myofibroblast areas in open skin wounds.

@article{Ishiguro2009BasicFG,
  title={Basic fibroblast growth factor induces down-regulation of alpha-smooth muscle actin and reduction of myofibroblast areas in open skin wounds.},
  author={Shigeki Ishiguro and Yoshikiyo Akasaka and Hideko Kiguchi and Takeya Suzuki and Risa Imaizumi and Yukio Ishikawa and Kinji Ito and Toshiharu Ishii},
  journal={Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society},
  year={2009},
  volume={17 4},
  pages={617-25}
}
To examine the effects of basic fibroblast growth factor (bFGF) on the inhibition of alpha-smooth muscle actin (alpha-SMA) expression in dermal fibroblasts, we have established two dermal myofibroblastic cell lines positive for alpha-SMA (rat myofibroblasts [RMF] and rat myofibroblast-like [RMFL] cells) and one fibroblastic cell line negative for alpha-SMA… CONTINUE READING