Basic fibroblast growth factor: effects on matrix remodeling, receptor expression, and transduction pathway in human periosteal fibroblasts with FGFR2 gene mutation.

Abstract

The Crouzon syndrome, which is associated with fibroblast growth factor receptor (FGFR2) mutations, is characterized by premature fusion of cranial sutures. We used an in vitro model of cultured periosteal fibroblasts from normal subjects and from Crouzon patients with FGFR2 mutation. We analyzed the matrix turnover rate and the effects of adding FGF2 by… (More)

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Cite this paper

@article{Bodo2002BasicFG, title={Basic fibroblast growth factor: effects on matrix remodeling, receptor expression, and transduction pathway in human periosteal fibroblasts with FGFR2 gene mutation.}, author={Maria Bodo and Cinzia Lilli and Maria Cristina Aisa and Luca Scapoli and Catia Bellucci and Eliana Rinaldi and Lara Tosi and Tiziano Baroni and Carmela Conte and Silvia Bellocchio and Francesco Carinci and Giordano Stabellini and Paolo Carinci}, journal={Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research}, year={2002}, volume={22 6}, pages={621-30} }