Basic fibroblast growth factor: increased gene expression in inherited and light-induced photoreceptor degeneration.

@article{Gao1996BasicFG,
  title={Basic fibroblast growth factor: increased gene expression in inherited and light-induced photoreceptor degeneration.},
  author={Hua Gao and Joe G. Hollyfield},
  journal={Experimental eye research},
  year={1996},
  volume={62 2},
  pages={181-9}
}
In a recent study, we reported that bFGF content and mRNA expression levels are elevated in degenerating photoreceptors in the rd mouse retina as compared to the levels in photoreceptors in age matched normal retinas (Gao and Hollyfield, 1995). To determine whether bFGF up-regulation is a general feature of degenerating photoreceptors, bFGF expression was examined with in situ hybridization in several rodent models with retinal degeneration: (a) the normal mouse retina in which cGMP metabolism… CONTINUE READING