Basic concepts and practical applications of recombinant DNA techniques in detection of human papillomavirus (HPV) infection. Review article.

@article{Syrjnen1990BasicCA,
  title={Basic concepts and practical applications of recombinant DNA techniques in detection of human papillomavirus (HPV) infection. Review article.},
  author={Stina M Syrj{\"a}nen},
  journal={APMIS : acta pathologica, microbiologica, et immunologica Scandinavica},
  year={1990},
  volume={98 2},
  pages={95-110}
}
Recent studies on the role of infectious agents in the pathogenesis of malignancy have demonstrated a strong association between HPV and several human benign and malignant epithelial neoplasms. There are 60 distinct types of HPV, of which HPV 16, 18, 31, 33, 35 and 39 have been associated with squamous cell neoplasia of the genital tract. Rapid progress in the field of recombinant DNA technology with the availability of specific probes has enabled the detection of HPV genomic sequences in… CONTINUE READING

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